Carcinoma Ovary Metastasis to Breast

Abstract

Abstract

Ovarian cancer commonly metastasises to lymph nodes, lung and liver. Primary ovarian carcinoma metastasising to breast is a very unusual and very few cases are described. Literature reports only 39 cases till date. Most common histological variety of Primary ovarian cancer metastasising to breast is papillary serous adenocarcinoma. Metastasis to breast suggests distant spread of the tumour and hence poor prognosis with median age of survival being 6 months from the date of diagnosis of breast metastasis. Although metastasis of ovarian carcinoma to breast is rare there should always be high index of suspicion during follow up of patient with ovarian cancer. Differentiation between primary and metastatic cancer of breast is important as treatment plan changes completely. We report a case of 60 year old female patient of papillary serous adenocarcinoma of ovary metastasising to breast. Patient developed breast metastasis after 1 year of completion of treatment for primary ovarian cancer. Her histopathology was suggestive of adenocarcinoma with immunohistochemistry positive for metastatic ovarian carcinoma. She was started on chemotherapeutic agents but died of disseminated disease within one year of initiation of treatment.

Keywords: Carcinoma ovary, metastasis, breast, adenocarcinoma, prognosis

Cite this Article

Rajnish Nagarkar, Tejashree Deshpande, Shrikant Suryavanshi et al. Carcinoma Ovary Metastasis to Breast. Research & Reviews: Journal of Oncology & Hematology. 2016; 5(2): 6–10p.