Synthesis, Characterization of Novel 5-(Dimethylamino) Naphthalene Sulfonamide Derivatives

Abstract

5-(Dimethylamino) naphthalene-1-sulphonic acid was synthesized by methylation of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulphonyl chloride were synthesized by the chlorination of 5-amino naphthalene-1-sulphonic acid. 5-(Dimethylamino) naphthalene-1-sulfonamide derivatives were synthesized by condensation of
5-(Dimethylamino) naphthalene-1-sulphonyl chloride and corresponding primary amines. There chemical structures were confirmed by I. R., ¹HNMR and elemental analysis.

Keywords: Synthesis, sulfonamides derivatives, 5-(Dimethylamino) naphthalene-1-sulphonic acid, 5-(Dimethylamino) naphthalene-1-sulphonyl chloride

Cite this Article

Khan Asif, Mishra Ritesh, Malvia Hitesh, et al. Synthesis, characterization of novel 5-(Dimethylamino) naphtha-lene sulfonamide derivatives. Research & Reviews: A Journal of Drug Design & Discovery. 2015; 2(2): 1–5p.