Case Report: A Rare Case of Dermatofibrosarcoma Protuberans

Abstract

Dermatofibrosarcoma protuberans (DFSP) DFSP is a low grade cutaneous malignancy first described in 1890 by Taylor. Darier was credited with establishing DFSP as a clinicopathologic entity in 1924 and HOFFMAN established the term in 1925.Clinical diagnosis requires a high index of suspicion because the lesion often has a fairly innocuous gross appearance. After biopsy or excision, expert pathological assessment with focused immunohistochemistry testing is essential to differentiate DFSP with other superficial tissue neoplasma. Dermatofibrosarcoma protuberans (DFSP) is a rare type malignant peripheral nerve sheath tumor, a soft tissue sarcoma that develops in the deep layer of skin. DFSP most often start as a small, firm patch of skin. The tumor typically grows very slowly (over months to years) and can become a raised nodule. DFSP morphologic studies revealed highly irregular borders with fingerlike extension into surrounding tissue. DFSP rarely metastasize there is propensity for local recurrence that may be associated with substantial morbidity.

Keywords: Dermatofibrosarcoma protuberans, malignancy, tumor, pathological assessment

Cite this Article

Rohit Dadhich, Kalpana Shridhar. Case Report: A Rare Case of Dermatofibrosarcoma Protuberans. Research & Reviews: Journal of Oncology & Hematology. 2017; 6(1): 17–23p.