Estimation of Amoxicillin Trihydrate and Ciprofloxacin Hydrochloride from Different Marketed Brands of Tablets by UV Spectroscopy
Abstract
Abstract
In the present work percentage of drug content of Amoxicillin trihyadrate and Ciprofloxacin from the marketed brands of tablets was estimated by UV spectrophotometer. Three different brands of tablets each of Amoxicillin (Mox, Novamox and Erox) and Ciprofloxacin (Cifran, Ciplox and Microflox) are purchased from the retail drug store and all the brands of tablets of Amoxicillin and Ciprofloxacin drug content was estimated from the standard calibration curve of both the drugs in phosphate buffer pH 1.2. Amoxicillin has lambda max of 246.5 nm with beer’s range of 10–40 µg/ml and ciprofloxacin has lambda max of 276 nm with beer’s range of 5–30 µg/ml. Percentage drug content of all the three brands of tablets was estimated from the standard calibration curve of respective drugs. From this work it was concluded that all the brands of tablets of amoxicillin and ciprofloxacin were found to within the standard limits of drug content specifications.
Keywords: UV spectroscopy, Amoxicillin trihydrate and Ciprofloxacin
Cite this Article
Sandeep DS, Narayana CR. Estimation of Amoxicillin Trihydrate and Ciprofloxacin Hydrochloride from Different Marketed Brands of Tablets by UV Spectroscopy. Research & Reviews: A Journal of Drug Design & Discovery. 2016; 3(1): 31–34p.
Downloads
Published
Issue
Section
License
Copyright Transfer and Declaration Form (Please compile this form, sign and send by e-mail and post)
Journal Title:
Title of the Paper:
Corresponding Author’s Information: Name: Address:
E-mail:
Contact Number: I
t is herein agreed that: The copyright to the above-listed unpublished and original article is transferred to STM Journals. This copyright transfer covers the exclusive right to reproduce and distribute the contribution, including reprints, translations, photographic reproductions, microform, electronic form (offline, online), or any other reproductions of similar nature. I/We declare that above manuscript is not published already in part or whole (except in the form of abstract) in any journal or magazine for private or public circulation, and, is not under consideration of publication elsewhere. I/ We warrant(s) that his/her/their contribution is original, except for such excerpts from copyrighted works as may be included with the permission of the copyright holder and author thereof, that it contains no libelous statements, and does not infringe on any copyright, trademark, patent, statutory right, or propriety right of others. I/We will not publish his/her/their above said contribution anywhere else without the prior written permission of the publisher unless it has been changed substantially.I/We also agree to the authorship of the article in the following order:Author(s) Name Signature(s)1. ________________2. ________________3. ________________4. ________________The author(s) agree to the terms of this Copyright Notice, which will apply to this submission if and when it is published by this journal (comments if any to the editor can be added below).
